Natural and recombinant human glycodelin activate a proapoptotic gene cascade in monocyte cells
نویسندگان
چکیده
منابع مشابه
Natural and recombinant human glycodelin activate a proapoptotic gene cascade in monocyte cells.
Glycodelin-A (GdA) is a member of the superfamily of lipocalins and the predominant glycoprotein secreted by human and primate endometrium in the secretory and early pregnancy phases. GdA can inhibit NK cell activity, T cell proliferation, and chemotaxis of monocytes. Its physiological function is thought to mediate immunotolerance at the fetomaternal interface. In the present studies, we engin...
متن کاملNatural and recombinant human glycodelin activates a proapoptotic gene cascade in monocyte cells
Glycodelin-A (GdA) is a member of the superfamily of lipocalins and the predominant glycoprotein secreted by human and primate endometrium in the secretory and early pregnancy phases. GdA can inhibit NK cell activity, T cell proliferation, and chemotaxis of monocytes. Its physiological function is thought to mediate immunotolerance at the fetomaternal interface. In the present studies, we engin...
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ژورنال
عنوان ژورنال: Journal of Leukocyte Biology
سال: 2008
ISSN: 0741-5400
DOI: 10.1189/jlb.0406291